Ctgf ligament

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August undefined, 2024

WebDec 1, 2024 · Connective tissue growth factor (CTGF), also known as CCN2, is a member of the CCN family and is a secreted matricellular and multifunctional protein. ... China) and … WebSep 15, 2024 · Objective: This work is aimed at revealing the role and the molecular mechanism of connective tissue growth factor 2 (CTGF) in the osteoblast differentiation …

Connective tissue growth factor promotes cell‐to‐cell communication …

WebApr 1, 2015 · Connective tissue growth factor (CTGF) is a downstream mediator of TGF-β. This study explores the effects of EMD and TGF-β1 on CTGF in periodontal ligament (PDL) fibroblasts and their interactions in PDL proliferation and development. Methods: Human PDL cells were stimulated with EMD. To explore the effects of EMD and TGF-β1 … WebFeb 12, 2024 · Furthermore, connective tissue growth factor (CTGF) has been shown to promote tendon regeneration via the stimulation of endogenous tendon stem cells. Here, we evaluated the potential of CTGF to promote tenogenic differentiation of ASCs in vitro. Gene and protein expression, cell proliferation, and FAK and ERK1/2 signaling were assessed. ... how fast is the banshee

CTGF Promotes the Osteoblast Differentiation of Human …

WebConnective tissue growth factor (CTGF) is covalently bound to latent TGFβ and is sequestered in the pericellular matrix (PCM) on heparan sulfate. ... At 10 weeks, surgical destabilisation of the joint, by cutting the … WebSep 17, 2024 · Cell–cell communication is an essential process to respond to biological stimuli and sustain the micro environmental homeostasis of human periodontal ligament stem cells (hPDLSCs). Connective tissue growth factor (CTGF), a critical secreted matrix protein, exhibits significant tasks in regulating the cell-cell and cell-matrix interactions. WebThese tissues, including teeth, periodontal ligament, alveolar bones, and dental pulp, present cell types and mechanical properties with great heterogeneity, which is challenging to reproduce in vitro. ... Phase (B) A scaffold area with 600 μm microchannels and PLGA microspheres loaded with CTGF was seeded with hPDLSCs for periodontal ligament ... high end wood flooring interior design

Connective tissue growth factor contributes to joint …

Profibrotic mediators in tendon disease: a systematic review

WebNational Center for Biotechnology Information WebOct 5, 2005 · Important roles of CCN2/CTGF in the development and regeneration of periodontal tissue including theperiodontal ligament are suggested. BackgroundCCN2/CTGF is known to be involved in tooth germ development and periodontal tissue remodeling, as well as in mesenchymal tissue development and regeneration. In … highend wordpress theme reviewWebligament-derived cells Masahiro Asano1,2, Satoshi Kubota1, ... Connective tissue growth factor (CCN2/CTGF) is a cysteine-rich protein with a molecular weight of 36–38 kDa [1-3] and belongs to ... high end wood furniture

"WebJul 29, 2024 · The current study showed that CTGF could promote the recovery of an injured anterior cruciate ligament. It can upregulate mRNA and expression of TGF-β1, COL1, COL2, SOX9, and tissue inhibitor of TIMP-1, and downregulate mRNA and expression of MMP-13, suggesting that the curative effect of CTGF on injured rabbit ligaments is … " - Ctgf ligament

Ctgf ligament

Connective tissue growth factor promotes …

WebDec 1, 2024 · Objectives. To clarify the role of cellular communication network factor 2/connective tissue growth factor (CCN2/CTGF) in periodontal tissue regeneration by investigating, the proliferative and tubulogenic responses of human endothelial cells obtained from the periodontal ligament to CCN2/CTGF. WebJun 29, 2024 · Objective . This work is aimed at revealing the role and the molecular mechanism of connective tissue growth factor 2 (CTGF) in the osteoblast differentiation …

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WebDec 1, 2024 · Connective tissue growth factor (CTGF), also known as CCN2, is a member of the CCN family and is a secreted matricellular and multifunctional protein. ... China) and washed 10 times with PBS (pH 7.2) under sterile conditions. Then, the periodontal ligament tissues attached to the middle third of the roots were curetted …

WebJun 6, 2012 · CTGF is a secreted matricellular protein with very complex biology. It has been shown to modulate many signaling pathways leading to cell adhesion and migration, … WebJul 23, 2024 · The overall impact of ASCs and CTGF on early tendon healing response. The overall healing response was grossly compared among tendons from three repair groups …

WebThe impact of CTGF/CTGF+ASC treatment on tendon cell growth and differentiation. (a-d) Changes in relative abundance of genes involved in cell growth and differentiation in … WebSep 6, 2024 · Connective tissue growth factor (CTGF) is an important extracellular matrix protein for bone homeostasis and cell differentiation. The purpose of our study was to …

WebJul 23, 2024 · The overall impact of ASCs and CTGF on early tendon healing response. The overall healing response was grossly compared among tendons from three repair groups (N = 10 per group): Control (repaired ...

WebOct 13, 2024 · Connective tissue growth factor (CTGF) is a cysteine-rich peptide that exhibits platelet-derived growth factor (PDGF)-like biological and immunological … high end wood flooring typesWebDec 4, 2009 · Since fibrosis is observed in smokers’ gingiva, it was hypothesized that fibrosis was caused by nicotine in the periodontium. Therefore, in this study, we investigated the effects of nicotine on the induction of a profibrotic molecule, connective tissue growth factor (CCN2/CTGF), in human gingival fibroblasts (HGFs) and periodontal ligament … high end wood stoveWebPurpose: This study was undertaken to investigate the role of connective tissue growth factor (CTGF) in fibroblast-to-myofibroblast differentiation and fibroblast-mediated … how fast is the bismarckWebThe impact of CTGF/CTGF+ASC treatment on tendon cell growth and differentiation. (a-d) Changes in relative abundance of genes involved in cell growth and differentiation in flexor tendons 14 days ... high end work boots for menWebFull length CTGF can be proteolytically cleaved in certain tissues to yield N-terminal truncated isoforms, which, depending on the isoform, contain only the TSP type I and … how fast is the black mambaWebThe inﬂuence of connective tissue growth factor on rabbit ligament injury repair ... Methods: A rabbit ACL injury model was used to study the effect of CTGF on ligament recovery. how fast is the bentley continental gtWebJun 3, 2011 · Abstract. Highlights: {yields} CCN2/CTGF localizes to the ligament-to-bone interface, but is not to the midsubstance region of human anterior cruciate ligament (ACL). {yields} Mechanical stretch induces higher increase of CCN2/CTGF gene expression and protein secretion in ACL interface cells compared with ACL midsubstance cells. {yields} … high end wood floors