WebAnti-IRF4 antibody [EP5699] - BSA and Azide free (ab240071) Description: Rabbit … WebJan 19, 2024 · Interferon regulatory factor 4 (IRF4) is a transcription factor from the IRF factor family that exerts regulatory functions in the immune system and oncogenesis. However, the biological role of IRF4 in colon cancer is still unclear. The aim of this study is to investigate whether IRF4 participates in the immune response in colon cancer. Methods
IRF4 controls the positioning of mature B cells in the …
WebJan 1, 2015 · Anaplastic large cell lymphoma (ALCL) is a distinct entity of T-cell lymphoma that can be divided into 2 subtypes based on the presence of translocations involving the ALK gene (ALK + and ALK − ALCL). The interferon regulatory factor 4 (IRF4) is known to be highly expressed in both ALK + and ALK − ALCLs. However, the role of IRF4 in the … cgn3acsmr login rogers
Targeting advanced prostate cancer with STEAP1 chimeric …
WebApr 8, 2024 · Immunoglobulin-class distribution was evaluated within the PC population defined by the Blimp-1 + IRF4 + phenotype in flow cytometry in blood as well as lymphatic and non-lymphatic organs . A clear Blimp-1 + IRF4 + population was identified in all organs with highest frequencies in the spleen (1.93% ± 0.49) and the lung (1.97% ± 0.58, Figure ... WebJan 20, 2024 · IRF4 binds to the canonical IFN-stimulated response elements (ISREs) as a homodimer, and it engages erythroblast transformation-specific IRF composite elements (EICEs) and activating … WebAug 6, 2024 · Notably, an IRF4 rearrangement with a gain of the IRF4 gene was detected (panel I; FISH analysis with break-apart probes showed split red/green signals in 85% to 90% of tumor nuclei with a gain of the IRF4 gene, with an average of 3.5 and 3.4 red and green signals, respectively, per neoplastic cell; yellow arrows, normal alleles; red and green … cgn3 firmware