Lithoplocamia lithistoides

WebLithoplocamia lithistoides (Q2418850) From Wikidata. Jump to navigation Jump to search. species of sponge. edit. Language Label Description Also known as; English: … WebLithoplocamia is een geslacht van sponsdieren uit de klasse van de Demospongiae . For faster navigation, this Iframe is preloading the Wikiwand page for Lithoplocamia . Home

Synthesis of the analogs of plocabulin and their …

WebLithoplocamia lithistoides. Lithoplocamia lithistoides adalah spesies spons yang tergolong dalam kelas Demospongiae. Spesies ini juga merupakan bagian dari genus Lithoplocamia dan famili Raspailiidae. Nama ilmiah spesies ini pertama kali diterbitkan pada tahun 1922 oleh Dendy. Seperti spons pada umumnya, spesies ini memiliki tubuh … WebGenus: Lithoplocamia Species (6): L. atlantica – L. dolichosclera – L. indica – L. lithistoides – L. minor – L. tuberculata. Name . Lithoplocamia Dendy, 1922 References … darien ct shopping https://nechwork.com

Lithoplocamia lithistoides - Wikipedia

Web10 jul. 2013 · Paclitaxel is arguably the most well-known and commercially successful mitosis inhibitor; intriguingly, these new compounds isolated from the Madagascan sponge Lithoplocamia lithistoides show a distinct biochemical mechanism of … WebLithoplocamia Click on organism name to get more information. Lithoplocamia lithistoides Disclaimer: The NCBI taxonomy database is not an authoritative source for nomenclature or classification - please consult the relevant scientific literature for the most reliable information. Reference: ... WebPM050489 is an effective polyketone inhibitor of Microtubule/Tubulin that can be isolated from Madagascan sponge Lithoplocamia lithistoides. PM050489 inhibits mitosis with an IC50 value of 26.4 nM. PM050489 has antitumor activity and can be used in cancer research [1] [2] . PM050489 inhibits the activity of HT-29, A-549 and MDA-MB-231 cells ... darien ct town hall address

RePub, Erasmus University Repository: PM060184, a new tubulin

Category:Lithoplocamia lithistoides - Wikidata

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Lithoplocamia lithistoides

Abstract A147: MI130004, a new ADC with a payload of marine …

WebOvarian cancer (OC) is a life-threatening tumor and the deadliest among gynecological cancers in developed countries. First line treatment with a carboplatin/paclitaxel regime is initially... Web11 jun. 2024 · Lithoplocamia lithistoides Dendy, 1922. Accessed through: Odido, M.; Appeltans, W.; BelHassen, M.; Mussai, P.; Nsiangango, S.E.; Vandepitte, L.; Wambiji, …

Lithoplocamia lithistoides

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Web21 jan. 2024 · Kahalalide F has displayed potent cytotoxicity against cancer cells of the breast (BT-474, MCF7, MDA-231, and SK-BR-3), colon (HT29 and LoVo), liver (Hep G2), lung adenocarcinoma (A549), ovaries,... Web29 feb. 2016 · PM184 is a marine -derive drug found in a sponge called Lithoplocamia lithistoides. This drug candidate is a microtubule inhibitor that targets a protein called tubulin in a novel way. It blocks cancer growth by impairing cell division of tumour cells through the inhibition of a crucial process called mitosis.

Web11 dec. 2024 · At difference with the above cited phase II anticancer drugs, plocabulin (PM060184) is not an ADC but it is a Lithoplocamia lithistoides sponge-derived polyketide which acts as a very potent antimitotic agent, binding to a specific β-tubulin site with possible activity on tumors resistant to other tubulin inhibitors . Web17 mrt. 2024 · Plocabulin (PM060184/PM184, PharmaMar) is a compound of marine origin derived from the Madagascan sponge Lithoplocamia lithistoides. Plocabulin belongs to a family of tubulin-binding agents that inhibits tubulin polymerization by binding to the dimer’s end, with one of the highest known affinities among tubulin-binding agents.

Webde Voogd, N.J.; Alvarez, B.; Boury-Esnault, N.; Carballo, J.L.; Cárdenas, P.; Díaz, M.-C.; Dohrmann, M.; Downey, R.; Hajdu, E.; Hooper, J.N.A.; Kelly, M.; Klautau ... WebGlobal Biodiversity Information Facility. Free and Open Access to Biodiversity Data.

WebLithoplocamia lithistoides adalah spesies spons yang tergolong dalam kelas Demospongiae. Spesies ini juga merupakan bagian dari genus Lithoplocamia dan famili …

darien family medical center gaWeb1 apr. 2014 · Abstract. PM060184 belongs to a new family of tubulin-binding agents originally isolated from the marine sponge Lithoplocamia lithistoides. This compound … birth standing up videoWeb1 apr. 2014 · PM060184 belongs to a new family of tubulin-binding agents originally isolated from the marine sponge Lithoplocamia lithistoides. This compound is currently produced by total synthesis and is under evaluation in clinical … darien eyewear keene new hampshire• Lithoplocamia atlantica (Lévi & Vacelet, 1958) • Lithoplocamia dolichosclera Lévi & Lévi, 1983 • Lithoplocamia indica Pulitzer-Finali, 1993 • Lithoplocamia lithistoides Dendy, 1922 dariene coffee west babylon nyWeb1 nov. 2024 · Plocabulin, a marine natural polyketide isolated from the sponge Lithoplocamia lithistoides, is a novel and potent microtubule-destabilizing agent. Guided by the reported binding mode, several new analogs of plocabulin have been designed through removing the right aliphatic chain and further modifying on the group and the … darien empire of saltWebLithoplocamia lithistoidesis 'n sponsspesiein die taksonomiese indeling van die Demospongiae(gewone sponse). Die liggaam van die spons bestaan uit kieselnaaldeen … darien funeral home facebookWeb1 dec. 2015 · PM050489 is a tubulin-binding agent originally isolated from the marine sponge Lithoplocamia lithistoides. This compound binds with very high affinity to β-tubulin at a new site, disrupting the microtubule network and impairing its function during divison, which leads to mitotic aberrations. darien first county bank